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ea0022p786 | Thyroid | ECE2010

Effect of pentoxifylline and glucocorticoids on peripheral blood mononuclear cells proliferation and apoptosis in Graves' ophthalmopathy

Hlazkova Anastasiya , Melnik Irina , Danilova Larissa , Kosmacheva Svetlana , Goncharova Nataliya , Antipovich Denis , Kirilenko Janna

The phosphodiesterase inhibitor pentoxifylline (PTX) is known to have immunomodulatory effects in some autoimmune diseases. The aim of our study was to assess the influence of glucocorticoids monotherapy and additive treatment with PTX on peripheral blood mononuclear cells (PBMC) proliferation and apoptosis in patients with GravesÂ’ ophthalmopathy (GO).Eighteen patients with GO and 28 healthy controls were investigated. GO patients were divided into ...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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